The crush time or grinding time was defined as the time needed to obtain a fine powder (free or nearly free from chunks) for six tablets per tablet type, crushed or grinded one by one. The efficiency of the screwcap crushers was evaluated after 30, 60, 90, and 120 s, and that of manual grinders after 10, 20, 30, 40, 50, 60, and 90 s.Web